[학부 세미나] 3/24(금) Amin Piri(연세대학교 기계공학과) "Bioaerosol monitoring and detection techniques"

기계공학부 구성원들의 많은 관심과 참여 부탁드립니다.

▣ 제 목: Bioaerosol monitoring and detection techniques

▣ 연 사: Dr. Amin Piri

▣ 소 속: 연세대학교 기계공학과

▣ 일 시: 2023. 3. 24.(Fri) 16:00

▣ 장 소: 제2공학관 B040호

▣ 초 록

Bio-aerosols are suspension of biological particulate matter (PM) and include a wide range of living and non-living particles such as bacteria, virus and fungi. Exposure to bio-aerosols may lead to various health complications. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak in 2019 triggered global concern and emphasized the importance of virus monitoring. Currently, considerable efforts are being expended toward reliable detection and quantification of bio-aerosol. Air sampling is the first step toward characterizing viral exposure. Since many bio-detection techniques require bio-particles to be in a liquid suspended state, electrostatics aerosol-to-hydrosol (ATH) sampling is a favorable option. Electrostatic precipitation (EP) is an efficient technique because it causes less damage to viruses and has a greater relative recovery of viruses as well as a lower pressure drop. However, there are several challenges to properly evaluate bio-aerosol samples. Initially, the collection procedures must ensure the survival or biological activity of bio-particles during and after collection. On the other hand, even during a viral outbreak, there is a relatively low concentration of the virus in air (10³–10⁴viral genome copies/m³ ), which makes detection and monitoring very challenging because the limit of detection of most polymerase chain reaction (PCR) devices is approximately 10³viral genome copies/mL. In addition, the current bio-aerosol detection methods require sample preparation steps taken place in well-equipped laboratory facilities after air sampling and therefore, cannot meet the needs of rapid on-site detection. Thus, it is imperative to address these challenges for an efficient measurement of pathogenic bio-aerosols and prevention of future pandemics. In this seminar, the latest advances on bio-aerosol monitoring strategies involving development of efficient air samplers, liquid-phase high-throughput microfluidic chip-based enrichment devices and detection systems are introduced and an strategy for on-site continuous sampling and detection is proposed.